Less common but serious: pancreatitis, gallbladder disease, kidney injury, hypoglycemia (with other diabetes meds), worsening diabetic retinopathy, and rare allergic reactions
Avoid Retin-A, Renova, and Tazorac must not be used for 1 week before or after treatment
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How It Affects Melanin Niacinamide prevents melanin from transferring to skin cells rather than stopping its production
These canonical functions positioned DHODH primarily as a metabolic enzyme critical for nucleotide biosynthesis and cellular proliferation, before its more recent identification as a mitochondria-specific ferroptosis suppressor in select cancer contexts
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