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Many patients report a reduction in cravings not only for food but also for alcohol, nicotine, and other addictive behaviors
Phentermine is a controlled substance and is approved only for short-term use typically up to 12 weeks because tolerance builds relatively quickly and the appetite-suppressing effects diminish over time
Because of this, insulin therapy often leads to weight gain, not weight loss
Key finding: AOD 9604 (0.1-10 mcg/kg) promoted cartilage repair with 52% defect filling versus 8% in controls
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