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An under-dosed product will never achieve the target plasma concentration, making any half-life calculation irrelevant
N Engl J Med 348:21102124 Carta M, Murru L, Barabino E, Talani G, Sanna E, Biggio G (2008) Isoniazid-induced reduction in GABAergic neurotransmission alters the function of the cerebellar cortical circuit
Both the ipsilateral and the contralateral hemispheres responded similarly, with an increase in adult neurogenesis peaking at about 2 weeks and returning to baseline by 65 days after stroke
Recent studies based on machine learning identified different families of compounds already known to target SnCs, such as cardiac glycosides 38 or molecules mimicking the combination of dasatinib/quercetin 39 , confirming the real potential of this technique
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