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2 To combat oxidative damage, the thiol containing tri-peptide glutathione (GSH) plays a central role

Niacinamide improves uneven skin tone 3

Several medications including antibiotics, acid blockers, and oral contraceptives can interfere with absorption and increase excretion of B vitamins

And by promoting rapid and effective detoxification, glutathione greatly reduces our overall cellular exposure to toxins, many of which are known carcinogens

In addition, the transcription of the IGF-2 gene is similarly reduced by wild-type p53 (Zhang et al, 1996)

This is because the hormonal shifts that trigger fluid retention, like increased cortisol, happen relatively quickly