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Gastroenterology 140 , 10841091 (2011)

GLP-1 users typically fall into one of two groups based on their main motivation: In spite of this, what unites most consumers, is that GLP-1 therapy often brings major lifestyle changes

Frioux, C

Clinical trials show average weight loss of 15-20% of body weight over 68 weeks, though individual results vary based on genetics, adherence, and lifestyle

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If its real, says Pearce, its probably very very rare and very low risk. Nevertheless, Pearce suggests that American clinicians will likely continue to follow prescribing guidelines for medical-legal reasons, if nothing else. Fortunately only a tiny minority of people are affected by this warning