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Aggregation visible as cloudiness or particulate matter, failure to fully dissolve, or immediate precipitation after reconstitution suggests either degradation or the presence of contaminants that affect solubility

The 56-day window applies only after first use

Palpable lumps or thickening indicate developing lipohypertrophy

Post-hoc comparisons showed that the Firmicutes phylums relative abundance was significantly higher in WD control mice compared to mice in the vehicle- and 5A-1MQ-treated groups switched from WD to LD (Fig

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