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6 Positioning in guidelines In NICEs guideline on the management of type 2 diabetes in adults (NG28), SUs may be used first-line for rescue therapy in symptomatic hyperglycaemia, or if low cardiovascular risk and metformin intolerance/contraindication

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When people become dehydrated from vomiting, diarrhea, or simply drinking less because their appetite is low, saliva volume drops, and bacterial activity increases

Cureus , doi: 10.7759/cureus.77998 (2025)

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