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The presence of these cells with a direct mechanism for -cell killing suggests a pathological mechanism

Additionally, two-year safety data from the STEP 5 trial shows that while gastrointestinal events occurred in 82% of participants at some point during the study, most of these events were concentrated in the initial 6 months, with frequency and severity declining markedly in long-term treatment

16(7):72635 Neilson LM, Munshi KD, Peasah SK, Huang Y, Swart ECS, Henderson R et al (2021) Changes in type 2 diabetes medication utilization and costs in the United States, 20142019

It has mitochondrial effects

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