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Consistent sleep and wake times, a cool dark bedroom, limiting alcohol, avoiding caffeine after midday, and managing stress are the most consistently evidence-supported sleep hygiene strategies

However, more studies are needed

This dietary supplement should not be used as a substitute for a varied diet

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203 Therefore, reviews or intervention strategies discussing SIRT1 in MASLD must avoid the oversimplified assumption that SIRT1 activation is always beneficial and instead adopt a refined, stage- and cell-specific framework