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OVA-induced asthmatic mice were treated with low (10 mg/kg) or high (20 mg/kg) doses of luteolin and showed that high-dose luteolin significantly reduced airway resistance and improved lung function, with great improvement in inflammation, mucus secretion, and collagen deposition [160]
Conversely, enhancing axial effects through M2 TGF-, CAF-cysteine, and stearoyl-CoA desaturase 1 (SCD1) upregulation protects CSCs from ROS damage and maintains stem cell properties (55)
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