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Comprehensive circulatory metabolomics in ME/CFS reveals disrupted metabolism of acyl lipids and steroids

Wilkens, P., Scheel, I

Ma X, McKeen T, Zhang J, Ding WX

Suitability is determined during a medical consultation after a full assessment of medical history, goals, and individual health factors

Dosage escalation is designed to minimize side effects: Wegovy: Start at 0.25 mg weekly, gradually increase every 4 weeks until the maintenance dose of 2.4 mg is reached

In addition, clinicians must pay close attention to drug interactions, particularly with chemotherapy agents metabolized by cytochrome P450 enzymes, to prevent altered plasma drug concentrations