What NAPQI does: Directly binds to and damages cellular proteins Depletes glutathione rapidly Generates oxidative stress which damages DNA Triggers cell death Damages mitochondria, disrupting energy production NAPQI crosses the placenta and depletes fetal brain glutathione at doses below those causing maternal liver toxicity
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[DOI] [PMC free article] [PubMed] [Google Scholar] 272.Oguri M
Emerging therapeutic modality enhancing the efficiency of chemotherapeutic agents against head and neck squamous cell carcinoma cell lines
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