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Nausea, the most common adverse effect, likely reflects GLP-1 receptor activation in brainstem areas controlling emesis

Research indicates that the dual-agonist drugs may lead to more weight loss compared with drugs that activate a single hormone pathway

Vergs, M

In agreement with previous evidence from genetic models, these data show that chronic modulation of IGF-1R signaling may be most well suited for targeting aging in females 6,7,8 , rather than males

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