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Give each dose four full weeks before increasing

Even mild shifts in blood sugar levels can contribute to feeling tired, lightheaded or less alert

We used version 2 of the Cochrane risk-of-bias tool (ROB 2) to assess the risk of bias, conducted frequentist random-effects network meta-analyses and evaluated confidence in effect estimates utilising the Confidence In Network Meta-Analysis (CINeMA) framework

By binding to GLP-1 receptors throughout the body, semaglutide triggers multiple physiological responses that affect both glucose metabolism and appetite regulation