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Acknowledgements This work was supported in part by US National Institutes of Health (NIH)/National Institute of Mental Health grant R03MH076449 (D.L.W.) and by NIH/National Institute of Allergy and Infectious Diseases (NIAID) grant R01AI065622 (D.L.W.), and in part by the NIH Roadmap for Medical Research Molecular Libraries Program

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"It is particularly prevalent in high rainfall areas (450mm rain per year), where improved, irrigated or fertilised pastures can grow rapidly, such as a spring flush." Symptoms of clinical deficiency in young livestock include scouring

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In preclinical studies, it inhibited proliferation of a broad range of tumor cell lines (cell IC50 6.2 nM to 4.3 M) and inhibited HUVEC growth in response to HGF and VEGF as an in vitro model of angiogenesis [116]

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