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Natalie Telis, PhD

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doi: 10.1038/s41531-022-00428-2 23 RamakrishnaCMendoncaSRueggerPMKimJHBornemanJCantinEM

This approach may be particularly relevant for patients who have been on high doses for extended periods or who have concerns about abrupt changes in appetite or glucose control

You should not assume that one approved area will produce better weight loss than another

Semaglutide activates only GLP-1 receptors, whereas tirzepatide activates both GLP-1 and GIP receptors, offering dual-pathway signaling for potentially greater insulin sensitivity gains