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Furthermore, findings from a mouse model of unilateral ureteral obstruction suggest that NLRP3 promotes TGF- signaling, R-Smad activation, and epithelial-mesenchymal transition in renal tubular epithelial cells through a mechanism independent of its classical inflammasome function [199]

Broader epidemiology (LeRoith 2003

Higher levels of platelet-derived MPs, which correlate positively with fasting blood sugar and glycated hemoglobin, have been shown in newly diagnosed T2DM patients compared to healthy individuals (70)

The practical question is not only whether a symptom can happen