Excitotoxicity is a key neurodegenerative mechanism that disrupts neuronal function and survival in CNS disorders [139]
& Trigun, S
In this study, we have used liquid chromatography-tandem mass spectrometry (LC-MS/MS) to characterize NAPQI binding to human glutathione S -transferases (GSTs) in vitro
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doi: 10.1017/jns.2019.29 68 WangZWangHChenYChenYZhangXDiwonAet al
Alternatively, the intrinsic pathway mediates the effects of ROS and many other stimuli, such as hypoxia, toxins, and ischemia-reperfusion injury, that may evoke an apoptotic response, in part, due to ROS generation