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You may notice reduced appetite suppression during the gap, but blood levels will rebuild quickly once you resume

Skip dense, greasy, or hard-to-digest foods

Longer half-life means more drug overlap when you inject early

The FDA-reviewed clinical trials for semaglutide (SUSTAIN and SELECT series) tracked musculoskeletal side effects separately from joint pain

But there is one group of people who should pay extra attention to protein: those who take GLP-1 drugs (like Ozempic and Mounjaro for type 2 diabetes and Wegovy and Zepbound for weight management)