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Hypothalamic Interaction: Modulates hypothalamic nuclei involved in sleep and hormone release [Przewlocki 1983]

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Importance of both folic acid and vitamin B12 in reduction of risk of vascular disease

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In addition, certain medical conditions and medications can cause vitamin B12 deficiency (30)

doi:10.7860/JCDR/2016/18208.8127 If a good first response is seen, a second injection may be considered when the improvement from the first injection begins to taper off