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J Med Chem 58(18):737080 Merrifield BA (1963) Solid Phase Peptide Synthesis

Side effects frequently occur during dose escalation and may lessen over time, usually within the first few weeks to months

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These gastrointestinal effects are generally dose-dependent, mild to moderate in severity, and tend to improve within 8 to 12 weeks as the body adjusts

Claydon VE, Krassioukov AV

Sheth received grants from the National Institutes of Health, American Heart Association, and Hyperfine