Its only available in its branded form, and a generic alternative likely wont be available until the early 2030s
Post-translational modifications, especially those in the DNA binding domain of FOXO4 protein, appear to modify its functionality as a transcription factor and regulation of pathways such as apoptosis, cellular senescence, insulin signaling, and senescence
Think of it this way: GLP-1 medications are doing the heavy lifting on fat loss
doi:10.1006/bbrc.2002.6364 24
Randomised trials, often performed on patients in intensive care units with different medical conditions, and usually including patients with stress hyperglycaemia together with those with diabetes, have provided discordant results, with either reduced37 , 38, unchanged39, or increased40 mortality
Mechanism is not the same as outcome