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International guidelines highlight the need for more personalized treatment 1 , but the concept has not yet been systematically examined in randomized trials specifically designed to evaluate treatment responses in patients with different characteristics

They found that NAD+ supplementation normalized several Alzheimer's-related features, including synaptic plasticity, learning and memory deficits, and DNA damage responses

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Additional datasets analyzed during the current study are available from the corresponding author upon reasonable request

10.1016/j.biochi.2006.10.014 Biochimie 19 ChenL.YangH

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