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Ascorbic acid is a potent water soluble antioxidant capable of scavenging/neutralizing an array of reactive oxygen species viz., hydroxyl, alkoxyl, peroxyl, superoxide anion, hydroperoxyl radicals and reactive nitrogen radicals such as nitrogen di- oxide, nitroxide, peroxynitrite at very low concentrations [46]

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And the modulatory rather than stimulatory nature of its effects on systems like nitric oxide and inflammation suggests a lower risk of overcorrection compared to directionally-acting compounds

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Patients with higher initial BMI may experience greater absolute weight loss but similar percentage reductions compared to those with lower starting weights