[33, 34, 35, 36] Mechanism: Typically pre-renal, occurring in the setting of volume depletion from GI losses (nausea, vomiting, diarrhea, reduced oral intake) More frequently seen at higher, obesity-level doses Although generally reno-protective long term, post-marketing data describe acute rises in creatinine following days to weeks of significant GI symptoms Risk factors: Underlying chronic kidney disease Concomitant use of ACE inhibitors, ARBs, diuretics, or SGLT2 inhibitors ED Management: IV fluids Hold GLP-1 and contributing medications Usually reversible with supportive care Future Directions GLP-1 receptor agonists are rapidly evolving beyond their original indications in diabetes and obesity
This is just bringing demand to our practice to the next level
Smoothies can be helpful when chewing feels like too much: Blended snacks allow you to sip slowly, adjust thickness, and pause as needed, which can make protein intake feel more manageable
BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide a chain of 15 amino acids derived from a protective protein found in human gastric juice
Suspected adverse reactions to medicines including those received in clinical trials can also be reported via the MHRA Yellow Card Scheme at yellowcard.mhra.gov.uk
Cardiovascular and Respiratory Effects The cardiovascular system includes your heart and blood vessels