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Previous studies investigating TMAO responses after an OCC did not measure TMAO between 8 and 24 h and assumed T max occurred at 24 h ( max occurred before 24 h for pomegranate intervention, with a mean of 21.6 3.0 h (Table 3)

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This pre-meal timing also ensures that the insulin-sensitizing minerals are circulating in the bloodstream, ready to assist the cellular receptors as soon as the pancreas releases insulin in response to the meal