Dose may be titrated gradually and given up to twice a week depending on the condition and desired outcomes
doi: 10.1073/pnas.0813361106, 28 ChenB.WenX.JiangH.WangJ.SongN.XieJ.et al
Chen et al., 2022) with the dataset identifier PXD051998
N Engl J Med 314(23):14941497 Rocha JF, Vaz-Da-Silva M, Nunes T, Igreja B, Loureiro AI, Bonifcio MJ, Wright LC, Falco A, Almeida L, Soares-Da-Silva P (2012) Single-dose tolerability, pharmacokinetics, and pharmacodynamics of etamicastat (BIA 5453), a new dopamine -hydroxylase inhibitor, in healthy subjects
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