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IF has been shown to decrease LDL levels by 1 to 47 mg/dL, total cholesterol by 5 to 88 mg/dL, and TG by 364 mg/dL [28]

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In addition, they also encode various positive or negative regulatory factors related to pathogenicity, including RBF1, EFG1, and TUP1, as well as genes encoding secreted aspartic acid proteases involved in invading the host endothelial barrier and macrophage phagocytosis (Navarro-Garcia et al., 2001)