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The accumulating 1 -pyrroline-5-carboxylate can then be reduced to proline by the NADP(H)-dependent enzyme pyrroline-5-carboxylate reductase (PYCR or P5CR)

Call 999 or attend A&E if you experience these symptoms

[3] Healthcare providers may also exercise caution when prescribing these medications to individuals with kidney disease or a history of suicidal ideation or behavior

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Healing your gut is possible, but it takes great effort