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Therefore we believe nanomaterials with ultrasmall size (hydrodynamic diameter 0.05), indicating that Cu 5.4 O USNPs would not trigger obvious immune responses in vivo at the tested concentration

Specifically, isolated rats showed increased iron levels in the prefrontal cortex and decreased levels in the hippocampus compared with their group-housed counterparts

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The following comparison provides the key distinctions relevant to experimental design

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