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CVD Safety Semaglutide has a well-established FDA approval for reducing the risk of major adverse cardiovascular events (MACE) in high-risk patients, based on the SELECT trial which demonstrated a 20% reduction in MACE over a mean 39.8-month follow-up

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Instead, it seems likely that the DMSA's effect was due to the reduction of toxic metals in the RBC, allowing glutathione to return to a normal level

The study also noted a reduction in liver fat

Figure 4) (Van den Broeck et al., 2020)