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Overcoming resistance to combination radiation-immunotherapy: A focus on contributing pathways within the tumor microenvironment

These effects are mostly mild to moderate and tend to improve as the body adapts, but they are the leading reason patients reduce doses or discontinue treatment

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Qureshi AI, Saleem MA, Jadhav V, et al

Another case is that up to one-third of patients receiving immunotherapy experienced the well-known cytokine-release syndrome, which is a result of the powerful immune effector responses 7