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356 In the brain sample of AD patients, mitophagy levels decreased 3050% compared with the normal ones, at the meantime downregulated PINK1 and BNIP3L were observed

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According to the Centers for Disease Control and Prevention (CDC), early signs such as vomiting and fatigue develop within hours, while severe cases progress to jaundice, confusion, and multi-organ failure if untreated

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After completion of the initial l-carnitine or BB challenge (baseline or visit 1), an ensuing week-long treatment of oral antibiotics (7) was given to suppress intestinal microbiota, and the challenge (d 3 -l-carnitine or d 9 -BB) was then repeated (visit 2)