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PERMP total score results from the sum of the number of math problems attempted plus the number of math problems answered correctly

This steady-state accumulation allows efficacy to build over the first four to five weeks of treatment as drug concentrations reach plateau levels

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"Compounded drugs can be important for overcoming shortages or meeting unique patient needs - but compounders should not try to compound drugs in a way that circumvents [the] FDA's approval process." Under US regulations, compounding pharmacies can make and sell medicines - even if they are still under patent - if supplies are limited in the marketplace