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Food and Drug Administration's decision in December 2024 to approve Zepbound (tirzepetide) as the first drug to treat sleep apnea in adults with obesity

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Chiechio S, Copani A, Gereau RW, Nicoletti F

Its copper-mediated influence on lysyl oxidase activity, an enzyme critical to collagen cross-linking, is one proposed mechanism underlying these observations

doi: 10.1530/JME-19-0095

On day 2 (24 h after conditioning), rats were again given hormone treatment and then individually transported, in a clean, unused, transparent cage, back to the testing room 30 minutes after injection