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administering bacteriostatic water alone or in excessive volume could result in serious complications (such as hemolysis or fluid imbalance)

One of the most important studies was published in 2015

doi: 10.1002/lio2.746

In summary, genetic risk factors for development of serious DILI at relatively low levels of APAP overdose seem likely to exist but the limited studies performed to date need to be followed up by genome-wide approaches using larger numbers of confirmed DILI cases or possibly further studies on volunteers showing transient ALT elevation

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The rise, announced by manufacturer Eli Lilly in August 2025, means that Mounjaro will be more expensive to access privately in the UK from September 2025, but those who have an NHS prescription will not be affected by the rise