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Park et al., 2021)

The statement and its recommendations were endorsed by the American Association of Clinical Endocrinology, Association of Diabetes Care and Education Specialists, Breakthrough T1D, Advanced Technologies & Treatments for Diabetes, the International Society for Pediatric and Adolescent Diabetes, and the International Diabetes Federation Europe

24 In this regard, prohormone convertase enzymes cleave proglucagon into several small peptides including glicentin, glicentin-related pancreatic polypeptide, glucagon, oxyntomodulin and GLP-1

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Category 2 substances also have sufficient supporting information, but the FDA has identified significant safety risks

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