HAPPY GUT: Wellness starts in the gut, and we make it delicious
ET, view the manuscript online
low-dose tricyclic antidepressants (e.g., amitriptyline 10mg at night, with gradual titration) for pain and altered motility For IBS-C : Laxatives such as macrogols (polyethylene glycol)
This long half-life allows once-weekly subcutaneous retatrutide dosing and supports sustained metabolic activity between injections
Here are some of the most important micronutrients to support your body during weight loss: Vitamin A & zinc Promote skin renewal, elasticity and immune function B vitamins (B6, B12 and folate) Support metabolism and aid in energy production Biotin Another B vitamin that supports healthy skin, hair and eyes Magnesium Reduces muscle cramps, supports relaxation and helps maintain blood sugar balance Calcium & Vitamin D Support strong bones and muscle function Selenium & iodine Essential for thyroid health and metabolism regulation Choline Supports brain health, liver function and fat metabolism Weight loss isnt just about how much you eat, but also what you eat
Abbreviations 5-HIAA: 5-Hydroxyindoleacetic acid 5-HT: Serotonin (5-hydroxytryptamine) BBB: Bloodbrain barrier BDNF: Brain-derived neurotrophic factor cAMP: Cyclic adenosine monophosphate CRH: Corticotropin-releasing hormone CRP: C-reactive protein DPP-4: Dipeptidyl peptidase-4 GABA: Gamma aminobutyric acid GLP-1: Glucagon-like peptide-1 GLP-1R: Glucagon-like-1 peptide receptor GLP-1RA: Glucagon-like-1 peptide receptor agonist HPA: Hypothalamicpituitaryadrenal axis Icv : Intracerebroventricular Ip : Intraperitoneal IL-1: Interleukin-1 beta IL-6: Interleukin-6 NF-B: Nuclear factor kappa-light-chain-enhancer of activated B cells NTS: Nucleus tractus solitarius PKA: Protein kinase A PPG: Preproglucagon PVN: Paraventricular nucleus SCFA: Short chain fatty acid T2DM: Type 2 diabetes mellitus TNF-: Tumor necrosis factor alpha VTA: Ventral tegmental area References Wang PS, Aguilar-Gaxiola S, Alonso J, Angermeyer MC, Borges G, Bromet EJ, et al
