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The concern is daily exposure over weeks and months

The MS/MS raw data were processed using SpectroMine software (v4.2.230428.52329) with the built-in Pulsar search engine against the UniProt FASTA database for peptide identification 66

In the renal impairment study, this was in part owing to disruption by the COVID-19 pandemic, with temporary closure of the two study centres

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10.1016/0022-510X(77)90075-2