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They dont address whats happening at the tissue level the cellular damage, the inflammation that wont shut off, the collagen that stopped rebuilding, the nerve signals that keep firing after the original injury is long gone

Malkova A, Kudryavtsev I, Starshinova A, Kudlay D, Zinchenko Y, Glushkova A, et al

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Furthermore, the progression to secondary GBMs appears to be associated with the accelerated proliferation of lower-grade gliomas

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Bachvarov, D