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Adjunctive therapies to insulin for type 1 diabetes mellitus (T1DM), including glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodiumglucose cotransporter-2 inhibitors (SGLT2is), may improve glycaemic control and reduce insulin requirements

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General cytoprotection supporting cellular health

The side effect profiles are very different because their mechanisms are different

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These findings were further corroborated by Western blot analysis, in which we observed increased -H2AX expression, decreased pNPM1 (T199) protein levels and increased expression of autophagosome LC3A/B proteins (Fig