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Glutathione, the brain's primary intracellular antioxidant, protects dopamine-producing neurons from reactive oxygen species and supports mitochondrial function

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This arm of the mechanism is also believed to drive PCSK9 degradation, which appears to lower LDL cholesterol in clinical readouts

Severe side effects are rare but include anaphylaxis (especially in those allergic to cobalt or B)

A finding that pre-existing antibodies for other coronaviruses correlate with the low incidence of symptomatic SARS-CoV-2 infection in children would support protection rather than a risk of disease enhancement 73