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the human RCTs that put it ahead of most brain-fog fads Chandrasekhar 2012 (~27.9% lower cortisol), Choudhary 2017 in the Journal of Dietary Supplements (better memory, attention and executive function), Salve 2019 and Gopukumar 2021

Research Background Research on DSIP has explored its effects on sleep spindle activity, delta wave amplitude, and cortisol modulation

Although it has ben studied in Phase I and II trials, these studies did not lead to an approval, likely due to its unclear risk-benefit profile

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Always consult a qualified healthcare professional regarding any medical concerns

First, it is an endogenous molecule: it circulates in human plasma at a concentration of roughly 200 ng/mL around age 20, declining to about 80 ng/mL by age 60, a fall that has been linked, at least associatively, to the general decline in tissue regenerative capacity with age