The SELECT trial, published in The Lancet (October 22, 2025), provides a landmark analysis confirming that the cardioprotective benefits of semaglutide extend beyond weight loss alone. The SELECT Trial: Study Overview The SELECT trial (NCT03574597) enrolled 17,604 participants aged 45 years and above across 41 countries and 804 sites
This should also include any vitamins, supplements, or herbal products
One possible mechanism is through the modulation of neurotransmitters involved in appetite regulation, such as dopamine and serotonin
Wegovy leads to an average weight loss of 15-20% after 68 weeks and is more effective than other weight-loss injections, like Saxenda
doi: 10.1002/biof.1399
Yes, higher doses are more likely to cause gastrointestinal side effects, including bloating