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Notably, the ALKIVIA study also demonstrated positive phase II/III results for VYVGART Hytrolu within idiopathic inflammatory myopathies, triggering its further development within this indication [253], for which efgartigimod is the FcRn antagonist with the most advanced clinical program as of January 2025

Titration from 0.25mg to 0.5mg over 710 days allows receptor density to adjust, minimizing adverse events while building toward maintenance dosing of 0.51mg twice weekly

Ozempic is contraindicated in patients with a personal or family history of MTC and in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

Hypoglycaemia is uncommon when Mounjaro is used alone but may occur when combined with insulin or sulphonylureas

van den Hurk, C

[Abstract] Cell Discov