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The incretin hormone, glucagon-like peptide-1 (GLP-1), appears to be involved in both peripheral and central pathways mediating satiation

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When given at a daily dose of 5 nmol kg 1 , 7 days of treatment with GLP-1RA/tesaglitazar decreased body weight and food intake in DIO mice, while mice treated with the GLP-1RA showed no difference in either body weight or food intake relative to vehicle controls (Fig

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[DOI] [PMC free article] [PubMed] [Google Scholar] 12.Enatescu V.R., Kalinovic R., Vlad G., Nussbaum L.A., Hogea L., Enatescu I., Marinescu I., Ifteni P., Simu M., Marian C