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However, activation of the afferent branch of the vagus nerve by capsaicin or activation of the vagus nerve and ENS by exendin-4, another GLP-1RA, failed to increase NE concentrations (Fig

For weight management, NICE recommends specific GLP-1 agonists (TA875, TA664) for adults with a BMI of at least 35 kg/m (or 30 kg/m with weight-related comorbidities) and only through specialist weight management services

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M.LebherzC.et al (2014)

Conflict of interest FG received research support from Eli Lilly, LifeScan, and Takeda and served as a consultant and author for AstraZeneca, Boehringer Ingelheim, Eli Lilly, Merck Sharp and Dohme, Novo Nordisk, Roche Diabetes Care, and Sanofi