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Its also sourced from extrapolated animal research

Figure 2 Following oral administration, EGCG undergoes limited absorption by the intestines, resulting in minimal entry into the bloodstream and tissues (39)

PMID: 84 CatassiCElliLBonazBBoumaGCarroccioACastillejoGet al

ASCO GI Cancers Symposium, 2009

Simultaneously, the production of ketone bodies during fat metabolism can compete with uric acid for renal excretion, reducing the kidneys' ability to eliminate uric acid efficiently

[1] [2] Short-chain fatty acids (primarily acetic, propionic, and butyric acids), which microganisms form in the intestines, bind to the FFAR2 and FFAR3 receptors on K cells and L cells to stimulate their respective production and secretion of GIP [3] and GLP-1