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The secretion of adiponectin from adipose tissue enhanced by both incretins elicits a signal akin to a fasting state in hepatocytes through the cAMP/pAMPK pathway

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Moreover, the increased morbidity and mortality in patients with NASH is known to be closely related to the severity of liver fibrosis

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Orthostatic hypotension is specifically defined as a drop of 20 mmHg in systolic or 10 mmHg in diastolic blood pressure within 3 minutes of standing