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Patients on long-term metformin therapy should be monitored for vitamin B12 deficiency and may require supplementation

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2006 PMID: 16289566 Hadley ME, Dorr RT 2004 PMID: 15073503 Diamond LE, et al

Probiotics, prebiotics, and synbiotics modulate the gut-brain axis by influencing microbial composition, metabolic activity, immune responses, and neurochemical pathways

Significant Glucose Reduction: Evaluations of antidiabetic activity have shown that Moringa leaf extract significantly lowered blood glucose levels in diabetic rats, with effects comparable to insulin